UK Rep - UK Responsible Person

Qserve as your UK Rep, the UK Responsible Person for medical devices and IVD companies.

UK Responsible Person

When is a UK Rep required?

If your company is located outside Great Britain and you want to sell medical or in vitro diagnostic devices (IVDs) in England, Scotland, or Wales, appointing a UK Responsible Person (UK RP/UK Rep) is essential. A UK RP ensures your devices comply with UK regulations and is your liaison with the UK Health Authority and the Medicines & Healthcare Products Regulatory Agency (MHRA).

Since Brexit, medical device companies must meet additional regulatory requirements beyond the EU CE Marking to sell their devices in the UK. The UK RP plays a critical role in helping manufacturers navigate these changes by:

  • Registering your devices with the MHRA.
  • Ensuring your devices meet UK conformity requirements, including the UKCA marking, will become mandatory from July 2025.
  • Acting as the official point of contact between your company and the MHRA for regulatory matters.

After the UK left the EU in early 2020, medical device companies now face additional certification and in-country representation requirements beyond EU CE Marking to market their devices in the UK.

The MHRA published its last update on July 28th, 2023, and intends to introduce legislation to bring into force the transitional arrangements and post-market surveillance activities, as outlined in the government response on June 26th, 2022.  

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Responsibilities of the UK Responsible Person

  1. Documentation Review
    Verify the CE certificate (if applicable), the Declaration of Conformity (DoC), and technical documentation to ensure regulatory compliance.
  2. MHRA Registration
    Register your medical devices and IVDs in the MHRA database per UK requirements.
  3. Communication with MHRA
    Respond to all MHRA inquiries and provide necessary information and documentation to demonstrate device conformity.
  4. Samples and Device Access
    Forward MHRA requests for samples or device access, ensuring timely delivery or arrangements for access.
  5. Risk Mitigation
    Work with the MHRA to address and resolve risks associated with your devices. If elimination isn’t possible, implement measures to mitigate risks.
  6. Vigilance Communication
    Support complaint handling and incident reporting from healthcare professionals, patients, and users. Ensure compliance with vigilance reporting requirements through the MORE portal.
  7. Record Maintenance
    Maintain copies of technical documentation, the DoC, and relevant certificates (including amendments and supplements) for MHRA inspections.

Qserve’s UK RP Services
As your UK Responsible Person, Qserve will:

  • Verify and manage documentation such as the CE certificate, DoC, and technical files.
  • Act on your behalf with the MHRA to register devices and IVDs.
  • Prepare a robust regulatory strategy for UKCA marking and contact Notified Bodies for technical file review when applicable.
  • Ensure labeling conforms to UKCA standards.
  • Support vigilance reporting through the MORE portal to ensure post-market surveillance compliance.

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Qserve’s proven track record, diverse expertise, and commitment to supporting manufacturers ensure that your devices meet UK regulatory standards without unnecessary delays. Qserve simplifies your journey to the UK market from strategic planning to compliance management.

Let Qserve’s team of regulatory experts help you achieve seamless compliance and market access.

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Main Impacts for Manufacturers After Brexit

  1. UKCA Regulation Becomes Mandatory by July 2025
    • Starting in July 2025, the UK Conformity Assessment (UKCA) marking will be required for all medical devices and IVDs sold in the UK.
    • Grace Period: Until then, devices with the EU CE mark can still be sold on the UK market under transitional arrangements.

  2. MHRA Registration Required
    • All medical devices and IVDs sold in the UK must be registered with the Medicines and Healthcare Products Regulatory Agency (MHRA).
    • Manufacturers must appoint a UK Responsible Person (UK RP) to complete the registration process.

  3. Appoint a UK-Based Entity as UK Responsible Person
    • Non-UK manufacturers must designate a UK RP as soon as possible.
    • The UK RP liaises with the MHRA and ensures compliance with UK regulations.

  4. Registration Deadlines by Device Classification
    The registration deadlines vary depending on the classification of the device or IVD:

    Deadline

    Device/IVD class

    May 1st, 2021

    Class IIIs and Class IIbimplantables, all active implantable medical devicesAnnex II List A IVDs

    September 1st, 2021

    Class IIb non-implantable, all ClassIIadevicesIVDListB, and Self-test IVDs

    January 1st, 2022

    Class I devices and General IVDs.


  5. Devices Allowed Under Transitional Arrangements
    Until the UKCA marking becomes mandatory in July 2025, manufacturers can sell devices in compliance with the following EU directives and regulations:
    • Medical Device Directive (MDD)
    • Medical Device Regulation (MDR)
    • In Vitro Diagnostic Directive (IVDD)
    • In Vitro Diagnostic Regulation (IVDR)

  6. Labeling Requirements for UKCA-Marked Devices
    • The name and address of the UK Responsible Person must appear on the product labeling, outer packaging, or instructions for use if the device bears the UKCA marking.
    • The UK RP details are not required for CE-marked devices unless the device bears both CE and UKCA markings.

Manufacturers must act promptly to ensure compliance with post-Brexit UK regulations. This includes appointing a UK RP, registering devices with the MHRA, and preparing for the mandatory UKCA marking by July 2025.

Learn More About UK Medical Device Regulations

The Benefits of Engaging Qserve as Your UK RP
Partnering with Qserve as your UK Responsible Person provides distinct advantages:
  1. London-Based Entity: Qserve’s legal entity in London ensures compliance with UK RP requirements.
  2. Verified MHRA Access: Direct access to the MHRA database allows for prompt and accurate regulatory handling.
  3. Conflict-Free Service: As an independent party, Qserve avoids conflicts of interest, unlike distributors who manage multiple manufacturers.
  4. Regulatory Expertise:
    • Over 25 years of experience in regulatory affairs.
    • Expertise in UKCA marking, technical documentation, and MHRA requirements.
    • Comprehensive support for UKCA regulation compliance.
  5. Global Knowledge, Local Focus:
    • Combine international regulatory knowledge with personalized local service.
    • Stay updated on UK legislation changes to minimize the impact on your business.

     

All You Need To Know

Download the UK Responsible Person Leaflet

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Download Qserve UK Responsible Person leaflet